Welcome to CRS4 Digital Pathology Platform

This site provides documentation for the CRS4 Digital Pathology Platform (CDPP), an open-source system for managing whole slide image collections, structured annotation, and computational pathology workflows.

Platform overview

The CRS4 Digital Pathology Platform (CDPP) is an open-source software system designed to support digital pathology research through:

• Structured, multi-label morphological and clinical image annotation
• Support for controlled, customizable annotation protocols
• Annotation tools that enhance accuracy, efficiency, and consistency
• Workflow-based computational analysis with provenance tracking

CDPP is based on a modular architecture comprising:

• A slide repository (based on Open Microscopy’s OMERO)
• A virtual microscope for WSI viewing and interactive ROIs creation View on Github
• An annotation manager supporting both manual and AI-assisted annotation View on Github
• A workflow manager for automated image analysis (via Apache Airflow + CWL) View on Github

Its web-based interface supports distributed, protocol-driven collaboration and simplifies setup through Docker-based deployment.